Advancing Drug Discovery Projects more Efficiently from Bench to Bedside

Publications

  1. Lan L, Liu H, Smith AR, Appelman C, Yu J, Larsen S, Marquez RT, Wu X, Liu FY, Gao P, Gowthaman R, Karanicolas J, De Guzman RN, Rogers S, Aubé J, Neufeld KL, Xu L. Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins. BMC Cancer. 2018 Aug 10;18(1):809. doi: 10.1186/s12885-018-4704-z.
  2. Sun J, Chen Y, Li K, Huang Y, Fu X, Zhang X, Zhao W, Wei Y, Xu L, Zhang P, Venkataramanan R, Li S. A prodrug micellar carrier assembled from polymers with pendant farnesylthiosalicylic acid moieties for improved delivery of paclitaxel. Acta Biomater. 2016 Oct 1;43:282-291. doi: 10.1016/j.actbio.2016.07.014. Epub 2016 Jul 12.
  3. Wu X, Tang W, Marquez RT, Li K, Highfill CA, He F, Lian J, Lin J, Fuchs JR, Ji M, Li L, Xu L. Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling. Oncotarget. 2016 Mar 8;7(10):11708-23. doi: 10.18632/oncotarget.7336.
  4. Li K, Liu H, Gao W, Chen M, Zeng Y, Liu J, Xu L, Wu D. Mulberry-like dual-drug complicated nanocarriers assembled with apogossypolone amphiphilic starch micelles and doxorubicin hyaluronic acid nanoparticles for tumor combination and targeted therapy. Biomaterials. 2015 Jan;39:131-44. doi: 10.1016/j.biomaterials.2014.10.073. Epub 2014 Nov 16.
  5. Liu H, Li K, Xu L, Wu D. Bilayered near-infrared fluorescent nanoparticles based on low molecular weight PEI for tumor-targeted in vivo imaging. J Nanopart Res. 2014 Dec 16: 2784. https://doi.org/10.1007/s11051-014-2784-5.

2014
Zhang P, Huang Y, Liu H, Marquez RT, Lu J, Zhao W, Zhang X, Gao X, Li J, Venkataramanan R, Xu L, Li S. A PEG-Fmoc conjugate as a nanocarrier for paclitaxel. Biomaterials. 2014 Aug;35(25):7146-56. doi: 10.1016/j.biomaterials.2014.04.108. Epub 2014 May 22.

Lu J, Zhao W, Huang Y, Liu H, Marquez R, Gibbs RB, Li J, Venkataramanan R, Xu L, Li S, Li S. Targeted delivery of Doxorubicin by folic acid-decorated dual functional nanocarrier. Mol Pharm. 2014 Nov 3;11(11):4164-78. doi: 10.1021/mp500389v. Epub 2014 Sep 29.

Lu J, Zhao W, Liu H, Marquez R, Huang Y, Zhang Y, Li J, Xie W, Venkataramanan R, Xu L, Li S. An improved d-α-tocopherol-based nanocarrier for targeted delivery of doxorubicin with reversal of multidrug resistance. J Control Release. 2014 Dec 28;196:272-86. doi: 10.1016/j.jconrel.2014.10.016. Epub 2014 Oct 24.

Zhang X, Huang Y, Zhao W, Liu H, Marquez R, Lu J, Zhang P, Zhang Y, Li J, Gao X, Venkataramanan R, Xu L, Li S. Targeted delivery of anticancer agents via a dual function nanocarrier with an interfacial drug-interactive motif. Biomacromolecules. 2014 Nov 10;15(11):4326-35. doi: 10.1021/bm501339j. Epub 2014 Oct 28.

2013
Lu J, Huang Y, Zhao W, Marquez RT, Meng X, Li J, Gao X, Venkataramanan R, Wang Z, Li S. PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers. Biomaterials. 2013;34(5):1591-1600. PMC3529003

2011
Pan X, Thompson R, Meng X, Wu D, and Xu L. Tumor-targeted RNA-interference: functional non-viral nanovectors (pdf). Am J Cancer Res 2011;1(1):32-49.


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