Example of a near-infrared image overlayed with x-ray image of mouseExperimental and Preclinical Imaging Laboratory research activities include:

  • Measure drug efficacy by monitoring tumor growth of orthotopic/xenograft models by luminescence or fluorescence.
  • X-ray imaging in order to observe development of metastases in intracardiac injection or orthotopic transplantation models.
  • Bone Density Software for studying bone diseases, such as arthritis and osteoporosis, and measuring efficacy of drugs and other treatment options that may affect bone mineral and other densities. 
  • Monitor near IR fluorescent dyes in order to assess drug delivery via nanoparticles.
    • DiR: 750 nm ex, 780 nm em (more information)
    • IRDye┬« 800CW 2-DG (more information)
  • Delivery of near IR expression vectors to track gene of interest and/or tumor growth and in vivo target validation of molecular therapies.